|
|
MGM Home Page
Department Information
Departmental Contacts
Graduate Program
KUGR Genomics
Positions Open
Courses and Journal Clubs
Departmental Mission
and Organization
MGM Phone List
Faculty
Bryce Chackerian, Ph.D.
Vojo Deretic, Ph.D.
Jeremy S. Edwards, Ph.D.
Hattie Gresham, Ph.D.
Carolyn Mold, Ph.D.
Scott A. Ness, Ph.D.
Jac A. Nickoloff, Ph.D.
Mary Ann Osley, Ph.D.
Michelle A. Ozbun, Ph.D.
Antonito Panganiban, Ph.D.
David Peabody, Ph.D.
Roger Radloff, Ph.D.
Robert L. Rubin, Ph.D.
Stephanie Ruby, Ph.D.
Cosette Wheeler, Ph.D.
Research Faculty
John P. O'Rourke Jr., Ph.D.
Isabelle Vergne, Ph.D.
MGM News and Events
Chair's Special Recognition Award
Course Web Pages
BioMed 507
BioMed 514
Other Links
NM Scenes
Albuquerque
New Mexico
UNM Health Sciences Cntr
UNM
|
|
 |
|
Department of Molecular Genetics and Microbiology
 Stephanie Ruby, Ph.D.
Molecular Genetics and Microbiology
University of New Mexico HSC
915 Camino de Salud NE
Albuquerque, NM 87131
Office: CRTC 330
Tel: (505) 272-5830
Fax: (505) 272-6029
E-mail: sruby@unm.edu
Keywords: RNA splicing, snRNPs, spliceosome, regulation of gene expression, DNA-damage response, cancer biology, genomics
Research Interests
Regulation of eukaryotic gene expression in response to DNA damaging agents. Role of small ribonucleoproteins (snRNPs) in splice site recognition and splicing of nuclear precursor messenger RNAs. Intranuclear localization and nucleocytoplasmic transport of RNAs.
For information about post-doc positions in the Ruby lab, see Job Opportunities.
Recent Publications
Ruby, S.W. and J.W. Szostak. (1985) Specific yeast genes are expressed in response to DNA-damaging agents. Mol. Cell. Biol. 5:75.
Ruby, S.W. and J. Abelson. (1988) An early hierarchic role of U1 small nuclear ribonucleoprotein U1 in spliceosome assembly. Science 242:1028.
Ruby, S.W. and J. Abelson. (1991) Pre-mRNA splicing in yeast. Trends in Genetics 7:79.
Ruby, S.W., T.-H. Chang and J. Abelson. (1993) Four yeast spliceosomal proteins (PRP5, PRP9, PRP11 and PRT21) interact to promote U2 snRNP binding to pre-mRNA. Genes and Development 7:1909.
Ruby, S.W. (1997) Dynamics of the U1 small ribonucleoprotein during yeast spliceosome assemly. J. Biol. Chem. 272: 17333-17341.
Ruby, S.W. (1999). A yeast spliceosome assay. In Methods in Molecular Biology, Vol 118: RNA-Protein Interaction Protocols (Haynes, S.R., ed.) Humana Press, Inc. Tolowa, N.J. pp 323 349.
Ruby, S.W. (1999). Yeast pre-mRNA splicing extracts. In Methods in Molecular Biology, Vol 118: RNA-Protein Interaction Protocols (Haynes, S.R., ed.) Humana Press, Inc. Tolowa, N.J. pp 365-390.
Awasthi, S., R. Palmer, M. Castro, C.D. Mobarak, and S.W. Ruby (2001). New roles for the Snp1 and Exo84 proteins in yeast pre-mRNA splicing. J. Biological Chemistry 276:31004-31015.
Abu Dayyeh, B.K., T. Quon, M. Castro, and S.W. Ruby (2001). Probing interactions between the U2 snRNP and the DEAD-box protein, Prp5. (Submitted).
|
