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Sabrina Samudio-Ruiz

First Name: Sabrina
Last Name: Samudio-Ruiz
Credential Degree name College/
BA Biology University of Colorado Boulder 1999
PhD Biomedical Sciences University of New Mexico 2009
Department: Pharmaceutical Sciences
Role: Research Faculty
Start Date: 06/10/2009
I am currently research faculty in the UNM College of Pharmacy, Department of Pharmaceutical Sciences. In 2012, I was awarded a Mentored Research Scientist Development Award to Promote Diversity K01 from the National Cancer Institute (NCI). I am a full member of the UNM Cancer Center and participate in the Cancer genetics, Epigenetics and Genomics program. I also interact with several researchers in the UNM ovarian cancer group particularly my faculty mentor Dr. Laurie Hudson.
Primary Title: Research Assistant Professor
Primary Office: RIB 227
Primary Phone: 505-272-6932
I am a basic science researcher whose broad interests include intracellular signaling pathways, changes in gene expression and epigenetics; particularly how changes in these processes affect cancer progression. I am currently investigating epigenetic alterations and corresponding changes in gene expression associated with the development of platinum resistance in ovarian cancer cells. Platinum resistance in ovarian cancer patients is a major obstacle in clinical effectiveness and it occurs in a large majority of patients. Thus, our studies are aimed at understanding the mechanism behind the acquisition of platinum resistance and how we can target that mechanism in a cellular model. I am particularly interested in the role of the Epidermal Growth Factor Receptor and its downstream intracellular signaling pathways as we have previously shown that this receptor plays a role in the regulation of the epigenetic mechanism, DNA methylation. We believe this work to have high potential for clinical applications thereby leading our studies into more translational research in the future.

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