Pharmaceutics faculty use a variety of physicochemical, mathematical, and biologic approaches to elucidate mechanisms of drug delivery, evaluate the disposition and biologic activity of drugs and xenobiotics, and optimize therapeutic response.

 

Programmatic Research Goals and Objectives: 

• Develop strategies for effective delivery of pharmacologic agents to specific organs or intracellular targets

• Elucidate mechanisms governing drug transport and tissue disposition

• Examine pharmacokinetic factors that influence drug action

• Develop drug products for preclinical and clinical trials

Faculty 

 

Jamie G. Barnhill, Ph.D.: pharmacokinetics/pharmacodynamics of drug products; stability of dosage forms for the VA Cooperative Studies Program clinical trials activities

 

Linda A. Felton, Ph.D.: polymeric properties of coated dosage forms; transdermal penetration and skin deposition of chemicals; formulation development and GMP manufacturing of drug products for clinical trials

 

Donald A. Godwin, Ph.D.: mechanisms of dermal and transdermal penetration

 

Hugh D.C. Smyth, Ph.D.: pulmonary drug delivery systems, aerosol treatment and prevention of lung cancer, micro and nanoparticle drug delivery, respiratory delivery of drugs in cystic fibrosis. Smyth Lab website: www.aerosolresearch.com