Health Sciences Library & Informatics Center
MSC09 5100
1 University of New Mexico
Albuquerque, NM 87131-0001

Find Faculty at UNM Health Sciences Center

Bridget S Wilson, PhD

Contact Information:
505-272-4814
BWilson@salud.unm.edu

Department:
SOM Pathology Department

Education:
PhD :
University of New Mexico, (1989)
MS :
University of New Mexico, (1987)
BA :
Texas Tech University, (1974)

Interests:
Signal transduction through IgE Receptors (FcεRI) and ErbB family of growth factor receptors; Plasma membrane microdomains for signaling and internalization; Spatio-temporal aspects of cell signaling

The Wilson laboratory is interested in membrane organization and signal transduction. We use a variety of sophisticated techniques including:

  • Electron microscopy
  • Fluorescence microscopy, live cell imaging
  • Biochemical Assays
  • Recombinant protein design and expression
  • Mathematical Modeling through partnerships with Sandia Nat. Lab


Publications:
* S.Yang, M.A. Raymond-Stintz, W. Ying, J. Zhang, D.S. Lidke, S.L. Steinberg, L. Williams, J.M. Oliver, B.S. Wilson. (2007) Mapping ErbB receptors on breast cancer cell membranes during signal transduction. J. Cell Science In press.

* M Xue, G Hsieh, M Raymond-Stintz, S Steinberg, E Prossnitz, JM Oliver, D Lidke and BS Wilson. (2007) FPR and FcεRI occupy common domains for signaling and internalization. Mol. Biol. Cell 18:1410-1420

* Mean, S, T Mazel, A Smith, J Shadid, J Shepard, RJH Wojicikiewicz, G. Smith and BS Wilson. (2006) Reaction diffusion modeling of calcium dynamics with realistic ER geometry. Biophysical J. 91:537-557.

* BF Lillemeier, JR. Pfeiffer, Z Surviladze, BS Wilson and MM Davis. (2006) Plasma membrane-associated proteins are clustered into islands attached to the cytoskeleton. Proc. Natl. Acad. Sci. USA 103: 18992-18997.

* D. J. Frankel, J. Pfeiffer, J. M. Oliver, BS Wilson and A. R. Burns. (2006) Revealing the topography of cellular membrane domains by combined Atomic Force Microscopy/fluorescence Imaging. Biophysical J. 90: 2404-2413 (Cover).

* Wilson, BS, SL Steinberg, K Liederman, JR Pfeiffer, Z Surviladze, J Zhang, LE Samelson, LH Yang, PG Kotula and JM Oliver. (2004) Markers for detergent-resistant lipid rafts occupy distinct and dynamic domains in native membranes. Mol. Biol Cell 15: 2580-2592.

* Smith AJ, Surviladze Z, Gaudet EA, Backer JM, Mitchell CA, Wilson BS. (2001) p110 β and p110 δ PI-3 kinases upregulate upregulate Fc{epsilon}RI-activated Ca2+ influx by enhancing IP3 production. J. Biol. Chem. 276:17213-17220