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Research Associate Professor

Ph.D.; 1988; University of New Mexico; Albuquerque, NM; Medical Sciences
M.S.; 1967; Purdue University, West Lafayette, IN; Chemistry
B.A.; 1963; Holy Family College; Philadelphia, PA; Chemistry

Office: BRF 223H    Lab: BRF 227
Phone: (505) 272-5799
Email: dvanderjagt@salud.unm.edu

Description of research

Because of my background in analytical chemistry and nutrition, my research has focused on nutritional assessment in the context of disease, particularly in the developing world.
Recent work has centered on the nutritional status and body composition of children and adolescents with sickle cell disease (SCD). My recent grant submission to NIH proposes to examine the feasibility of using impedance analysis to monitor the effect of fatty acid supplementation in children with this disease. In addition, I have used both biochemical and physical measurements (such as calcaneal ultrasound) to determine the bone status in SCD and plan to examine the role of specific growth factors in the bone turnover in children with this disease.

The second area of interest is in the bone status of women residing in areas where the dietary intake of calcium is very low over a lifetime. In addition to establishing reference values for calcaneal ultrasound in a Nigerian population, I am also examining the effects that pregnancy and lactation have on the bone turnover in women with chronic low calcium intake. In relation to this, we are studying the effects of Norplant, a progesterone-only contraceptive, on the bone status of women using this form of implantable contraceptive.

A third area of interest is in the factors that contribute to anemia in sub-Saharan Africa, Nigeria in particular. The incidence of neural tube defects in northern Nigeria is one of the highest in the world. Because girls in this region of the world often marry after secondary school, we examined the folate and B12 status of girls attending government boarding schools. We determined that both their folate and vitamin B12 status was marginal to deficient. As a result of this study the local UNICEF program is incorporating folate supplementation into their vaccination programs and examining ways to increase locally available foods containing folate and vitamin B12 into the school menus. As an extension of this work, I am also interested in analyzing the locally available foods for their nutritional content since many of these foods are not contained in food data bases.

A new study is being implemented to determine the feasibility of using impedance analysis (phase angle, in particular) as a marker of the development of preeclampsia. Preeclampsia is a major contributor to maternal death in northern Nigeria where 25 to 30 per cent of women die during pregnancy and childbirth.

Selected publications

Glew RH, VanderJagt DJ, Glew RS, . Global Science Books. Plant Foods of West Africa: A Call for Bioavailability Studies. 85-87. Jun 2007.

Wang R, Tzamaloukas AH, Agaba EI, Servilla KS, VanderJagt DJ, Gibel Lj, Hartshorne MF, Change B. International Urology Nephrology. Management of Extreme Azotemia from Urinary tract obstruction without dialysis. Clinical Correlates and kinetic modeling of the recovery of renal function. 39(2). 587-593. Jan 2007. http://www.ncib.nlm.nih.gov/sites/entrez

VanderJagt DJ, Brock HS, Melah GS, Wl-Nafaty AU, Crossey MJ, Glew RH. J Health Popul. Nutr. Nutritional Factors Associated with Anemia in Pregnant Woman in Northern Nijeria . 1. 75-81. Mar 2007. http://www.ncbi.nlm.nih.gov/sites/entrez

Glew RH, McCarthy DM, Vanderjagt DJ. Acta Obstet Gynecol Scand. Vitamin B12 deficiency: is it underestimated in pregnant women. 85. 241-2. Jul 2006.Ikeh E, Glew RH, Vanderjagt DJ. Nigerian Journal of Health & Biomedical Sciences. Microbial and Trace Metal Content of Well Water in Three Rural Communities in Baucai State, Nigeria. 5. 66-70. Dec 2006.

Glew RH, Glew RS, Chuang LT, Huang YS, Millson M, Constans D, Vanderjagt DJ. Plant Foods Hum Nutr. Amino acid, mineral and fatty acid content of pumpkin seeds (Cucurbita spp) and Cyperus esculentus nuts in the Republic of Niger. 61. 51-56. Jul 2006.

Vanderjagt DJ, McCarthy DM, . Clinical Studies in Medical Biochemistry 3rd ed. Vitamin B12 Deficiency. 3rd. Oxford University Press, . 300-312. Jul 2006.

Vanderjagt DJ, Glew RH, . Clincical Studies in Medical Biochemistry. Calcium Deficiency Rickets. 3rd. Oxford University Press. 323-334. Jul 2006.

Glew RH, Herbein JH, Moya MH, Valdez JM, Obadofin M, Wark WA, Vanderjagt DJ. Clin Chim Acta. Trans fatty acids and conjugated linoleic acids in the milk of urban women and nomadic Fulani of northern Nigeria. 367. 48-54. May 2006.

Tzamaloukas AH, Murata GH, Vanderjagt DJ, Servilla KS, Glew RH. Adv Perit Dial. Lack of precision of indirect estimates of body water affects urea kinetic analysis in chronic peritoneal dialysis. 21. 13-16. Jul 2005.

Ujah IA, Aisien OA, Mutihir JT, Vanderjagt DJ, Glew RH, Uguru VE. Afr J Reprod Health. Factors contributin to maternal mortality in north-central Nigeria: a seventeen-year review. 9. 27-40. Dec 2005.

Glew RS, Vandejagt DJ, Chuang LT, Huang YS, Millson M, Glew RH. Plant Foods Hum Nutr. Nutrient content of four edible wild plants from west Africa. 60. 187-193. Dec 2005.

Vanderjagt DJ, Sagay AS, Imade GE, Farmer SE, Glew RH. Contraception. Effect of Norplant contraceptive on the bones of Nigerian women as assessed by quantitative ultrasound and serum markers of bone turnover. 72. 212-216. Sep 2005.

Glew RS, Vanderjagt DJ, Chuang LT, Huang YS, Millson M, Glew RH. Plant Foods Human Nutrition. Nutrient content of four edible wild plants form west Aftica. 60. 187-193. Dec 2005.

Vanderjagt DJ, Sagay AS, Imade GE, Farmer SE, Glew RH. Contraception. Effect of Norplant contraceptive on the bones of Nigerian women as assessed by quantitive ultrasound and serum markers of bone turnover. 72. 212-216. Sep 2005.

Bond B, Fernandez DR, Vanderjagt DJ, Williams M, Huang YS, Chuang LT, Millson M, Andrews R, Glew RH. Journal of Food Composition and analysis. Fatty acid, amino acid and trace mineral analysis of three complementary foods from Jos, Nigeria. 18. 675-690. Nov 2005.

Tzamaloukas AH, Rohrscheib M, Ing TS, Siamopoulos KC, Qualls C, Elisaf MS, VanderJagt DJ, Spalding CT. Int J Artif Organs. Serum potassium and acid-base parameters in severe dialysis-associated hyperglycemia treated with insulin therapy. 28. 229-36. Mar 2005.

Glew RH, Cole DM, Mehla GS, El-Nafaty AU, Crossey MJ, Tzamaloukas A, VanderJagt DJ. Clin Chim Acta. Lysosomal enzymes in preeclamptic women in northern Nigeria. 1-2. 95-101. Mar 2005.

Glew RS, VanderJagt DJ, Bosse R, Huang YS, Chuang LT, Glew RH, . Journal of Food Composition and Analysis. The nutrient content of three edible plants of the Republic of Niger. 18. 15-27. Feb 2005.

Glew RH, VanderJagt DJ. International Journal of Childbirth. The Antenatal Clinic at Gombe: Jewel of the Savannah. 20. 4-7. Jan 2005.

VanderJagt TA, Ikeh EI, Ujah IO, Belmonte J, Glew RH, VanderJagt DJ. Trop Med Int Health. Comparison of the OptiMAL rapid test and microscopy for detection of malaria in pregnant women in Nigeria. 1. 39-41. Jan 2005.

Ganga S, VanderJagt DJ, Obadofin MO, Stanley P, Zimmerman M, Skipper BJ, Glew RH. Journal of Investigative Medicine. Comparison of the clock test and a questionnaire-based test for demetia screening in Nigerians. 53. s82-s82. Jan 2005.

Glew RH, Kassam H, Vander Voort J, Agaba PA, Harkins M, VanderJagt DJ. J Trop Pediatr. Comparison of pulmonary function between children living in rural and urban areas in northern Nigeria. 50(4). 209-16. Aug 2004.

VanderJagt DJ, Damiani LA, Goodman TM, Ujah IO, Obadofin MO, Imade GE, Shatima DR, Glew RH. Bone. Assessment of the skeletal health of healthy Nigerian men and women using quantitative ultrasound. 35(2). 387-94. Aug 2004.

Glew Rh, Okolie H, Huang YS, Chuang LT, Suberu O, Crossey M, VanderJagt DJ. J Natl Med Assoc. Abnormalities in the fatty-acid composition of the serum phospholipids of stroke patients. 96(6). 826-32. Jun 2004.

Glew RH, Melah G, El-Nafaty AI, Brandt Y, Morris D, VanderJagt DJ. Clin Chim Acta. Plasma and urinary free amino acid concentrations in preeclampic women in northern Nigeria. 342(1-2). 179-85. Apr 2004.

Vanderjagt DJ, Patel RJ, El-Nafaty AU, Melah GS, Crossey MJ, Glew RH. Acta Obstet Gynoecol Scand. High-density lipoprotein and homocysteine levels correlate inversely in preeclamptic women in northern Nigeria. 83(6). 536-42. Jun 2004.

VanderJagt DJ, Mcclung KD, Kassamn HA, Harkins MS, Glew RH. J Natl Med Assoc. Pulmonary function of herdsmen. 96(4). 550-5. Apr 2004.

Glew RH, Brock HS, VanderVoort J, Agaba P, Harkins MS, VanderJagt DJ. J Trop Pediatr. Lung function and nutritional status of semi-nomadic Fulani children and adolescents in northern Nigeria. 50(1). 20-5. Feb 2004.

Glew RS, VanderJagt DJ, Huang YS, Chuang LT, Bosse R, Glew RH. Journal of Food Composition & Analysis. Nutritional analysis of the edible pit of Sclerocarya bierrea in the Republic of Niger (daniya, Hausa). 17(1). 99-111. Feb 2004.

Glew RH, Cole, DN, Mehla G, El-Nafaty AL, VanderJagt DJ, . Journal of Investigative Medicine. Lysosomal enzymes in preeclampsia in northern Nigeria. 52(1). 116-117. Jan 2004.

Glew RH, Casados JK, Huang YS, Chuang LT, VanderJagt DJ. Journal of Investigative Medicine. Correlation of the fatty acid composition and fluid property of the cholesteryl esters in the serum of Nigerian children with sickle sell disease and healthy controls. 52(1). 113-113. Jan 2004.

VanderJagt DJ, Trujillo MR, Bode-Thomas F, Huang YS, Chuang LT, and Glew RH. (2003) Phase angle correlates with n-3 fatty acids and cholesterol in red cells of Nigerian children with sickle cell disease. Lipids Health Dis 2: 2. Epub 2003 , May 06

Glew RH, Conn CA, Bhanji R, Calderon P, Barnes C, and VanderJagt DJ. (2003). Survey of the growth characteristics and body composition of Fulani children in a rural hamlet in northern Nigeria. J Trop Pediatr. 49: 313-22.

.VanderJagt DJ, Bonnett C, Okolo SN, and Glew RH. (2002). Assessment of the bone status of Nigerian children and adolescents with sickle cell disease using calcaneal ultrasound and serum markers of bone metabolism. Calcif Tissue Int. 71: 133-40.

Vanderjagt DJ, Huang YS, Chuang LT, Bonnett C, and Glew RH. (2002) Phase angle and n-3 polyunsaturated fatty acids in sickle cell disease. Arch Dis Child 87: 252-4.

VanderJagt DJ, Shores J, Okorodudu A, Okolo SN, and Glew RH. (2002). Hypocholesterolemia in Nigerian children with sickle cell disease. J Trop Pediatr. 48: 156-61.

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