The C/M core for cell culture work, histology and fluorescent microscopy of fixed samples is equipped with a cryostat, a fluorescent microscopy room for histology, a tissue culture room and basic instruments for cellular and molecular biology.

 

 

 

 

C/M Core Associate Directors:
  Ranjana Poddar, PhD
  Res. Assist. Prof. Neurology
  Email:  rpoddar@salud.unm.edu

   Surojit Paul, PhD
   Assistant Professor of Neurology
   Email:
   spaul@salud.unm.edu

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EPR Core houses:

1. a Bruker EleXsys E500 EPR spectrometer (9.5 GHz) equipped with a standard TE102 resonator, and variable temperature control system useful for measurement of small samples, such as chemical solution, tissue homogenate, tissue slice, and cultured cells;
2. a Bruker EleXsys E-540 EPR spectrometer equipped with a L-band bridge (1.0 GHz, low frequency) useful for in vivo imaging of free radical formations in the small animal models such as rat.
    

   Three resonators are available, depending on the nature of the study:

   1. imaging resonator for mouse or rat brain
   2. a 34 mm internal diameter birdcage resonator for in vivo studies with small animals such as mice and rats
   3. an external loop resonator for localized measurement on the specific site of an animal.

EPR Core Directors:
 John Weaver
 Research Asst Professor
 College of Pharmacy
 Email:
JMWeaver@salud.unm.edu

 Honglian Shi, PhD
 Research Associate Professor of
 Pharmaceutical Sciences
 Email: 
hshi@salud.unm.edu

MEG/EEG core has:

1. a 4-channel high-resolution MEG system (microSQUID) for in vitro and in vivo electrophysiology
2. a 128-channel EEG system
3. a multichannel system for intracortical extracellular electrophysiology.

MEG signals from a hippocampal slice can be measured without signal averaging.

The babySQUID is a novel magnetoencephalography system for neonates and infants. The major goal of this project is to establish the feasibility of obtaining new insights into brain functions of infants with healthy brains, patients with cerebral palsy and epilepsy by analyzing the spontaneous activity.

 

MEG/EEG Core Director:
  Yoshio Okada, PhD
  Professor of Neurology
  Email:  okada@unm.edu

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MRI core has a 4.7T 40 cm bore MR scanner for both structural and functional MRI in animal models, capable of T1, T2, T2* (BOLD), Perfusion Weighted Imaging (PWI), Diffusion Weighted Imaging (DWI), Diffusion Tensor Imaging (DTI).

• Surgical core has three operating rooms for acute and survival surgery of small and large animals.
• They are fully equipped. An autoclave is available for sterilizing instruments. There are two stereotaxic stations with microscopes for microscopic surgery. A Doppler is available for measuring blood flow.
   
• Both acute and longitudinal studies are possible.