Antonito Panganiban, Ph.D.
Molecular Genetics and Microbiology
University of New Mexico HSC
915 Camino de Salud NE
Albuquerque, NM 87131
 
Office: CRF 305
Tel: (505) 272-4214
Fax: (505) 272-9912
E-mail: apanganiban@salud.unm.edu

Keywords: virology, HIV, RNA structure, assembly

Research Interests

Retroviruses are single-stranded RNA viruses that infect a variety of vertebrate cells and replicate through a DNA intermediate. The research in my laboratory focuses on the molecular mechanisms that are required for retrovirus replication. Research in my lab is currently centered around two topics. We are investigating the mechanism by which virus particles are able to efficiently exit virus-producing cells. In addition, we are examining the role that higher order RNA structure plays in successful replication of the viral nucleic acid.

For information about post-doc positions in the Panganiban lab, see Job Opportunities.

Go to: Panganiban Lab Web Pages

Recent Publications

Sakuragi J, Shioda T, Panganiban AT.  Duplication of the primary encapsidation and dimer linkage region of human immunodeficiency virus type 1 RNA results in the appearance of monomeric RNA in virions. J Virol. 2001 Mar;75(6):2557-65.

Callahan, M.A., M. A. Handley , Y. H. Lee , K. J. Talbot , J. W. Harper, and A. T. Panganiban. 1998. Functional interaction of human immunodeficiency virus type 1 Vpu and Gag with a novel member of the tetratricopeptide repeat protein family. J. Virol. 72:5189-97.

Schwartz, M. D., D. Fiore, and A. T. Panganiban. 1997. Distinct functions and requirements for the Cys-His boxes of the human immunodeficiency virus type 1 nucleocapsid protein during RNA encapsidation and replication. J. Virol. 71:9295-9305.

Hoglund, S., A. Ohagen, J. Goncalves, A. T. Panganiban , and D. Gabuzda. 1997. Ultrastructure of HIV-1 genomic RNA. Virology 233:271-9.

McBride, M. S. , M. D. Schwartz, and A. T. Panganiban. 1997. Efficient encapsidation of human immunodeficiency virus type 1 vectors and further characterization of cis elements required for encapsidation. J. Virol. 71:4544-54.

M. S. McBride and A. T. Panganiban . 1997. Position dependence of functional hairpins important for human immunodeficiency virus type 1 RNA encapsidation in vivo. J Virol. 71:2050-8.