The Department of Pathology anticipates an ongoing need for postdoctoral fellows and seeks applications for positions in the following research areas listed below.
Cell Adhesion and Drug Design
Richard Larson, M.D.
The laboratory is developing new approaches for the analysis of cell and ligand binding as well as drug development. The laboratory is also focusing on development of several novel ligand-based technologies using nanoparticles and biosensors. We have recently developed new antagonists for possible therapeutic use. Minimum requirement: Ph.D. in related area of cell or molecular biology, immunology, physical chemistry, biophysics, or engineering. Postdoctoral applicants with cellular, biochemical, molecular, clinical or biophysical background is desired. Preference will be given to applicants with experience in leukocyte biology, computational drug development, cell adhesion and/or in vivo mouse studies.
Cell Signal Transduction, Leukemia, & Genomics
Cheryl Willman, M.D.
This research laboratory is engaged in fundamental studies of lymphoid and myeloid cell signal transduction and fundamental and translational studies of human leukemogenesis. Specific projects include:
Molecular Virology
Brian Hjelle, M.D.
The applicant will work in collaboration with a core of scientists who will study genetic vaccines, pathogenesis and molecular epidemiology of zoonotic viral pathogens. The successful candidate will develop animal and/or cell culture models for pathogenesis, a number of which will require Biosafety Level 3 containment. A wide range of methods will need to be employed, including neutralization tests for viral antibodies, preparation of tissues for pathologic studies and immunostaining, PCR, and DNA sequencing. Minimum requirements: (1) Ph.D. and/or M.D., or equivalent in a biological discipline; (2) Two or more years of virology experience (can include predoctoral training) using modern immunologic and/or molecular methods. Experience with biologically hazardous microbes is desired.
Rab GTPases in Trafficking, Kidney Disease, Neuropathies, Cancer and Drug Discovery
Angela Wandinger-Ness, Ph.D.
Postdoctoral positions available to study intracellular membrane transport and alterations that underlie neuropathies, epithelial cancers and kidney disease. Our interactive research group is elucidating the functions of several rab GTPases and other regulatory molecules in exo- and endocytic membrane transport. Deficits in the proper localization and function of Rab7 is of key importance in growth factor receptor signaling that when defective contributes to cancer and peripheral neuropathies. Alterations in ciliary trafficking regulated by a complex of small GTPases contributes to pathophysiology of autosomal dominant polycystic kidney disease. In collaboration with the UNM Molecular Libraries Screening Center we are identifying small molecules targeted to the Rab GTPases. Our laboratory utilizes integrated, state of the art approaches to tackle these questions, employing laser scanning confocal microscopy, flow cytometry, protein biochemistry, and genomic strategies. Qualified applicants should have a Ph.D. in biology or life sciences. Experience in cell and molecular biology, and protein biochemistry are encouraged.
Signal Transduction and Cell Adhesion
Larry Sklar, Ph.D., Bruce Edwards, Ph.D.
The laboratory is developing new approaches for the real-time analysis of ligand binding and macromolecular assembly including rapid kinetic flow cytometry with applications in high throughput screening for drug discovery. Applications include signal transduction and cell adhesion systems as well as flow cytometric analysis of molecular assemblies on beads. Minimum requirement: Ph.D. in related area of cell or molecular biology, immunology, physical chemistry, biophysics, or engineering. Postdoctoral applicants with cellular, biochemical, molecular, clinical or biophysical background is desired. Preference will be given to applicants with experience in signal transduction, cell adhesion, and/or development of novel flow cytometry instrumentation.
Signal Transduction, Innovative Imaging, Quantitative Biology & Modeling
Janet Oliver, Ph.D., Professor, Bridget Wilson, Ph.D., Professor, Diane Lidke, Ph.D., Assistant Professor
Position available in signaling group consisting of three core faculty, graduate students, postdoctoral fellows, and technicians. This is a multi-disciplinary group, with projects in 1) IgE receptor-mediated signaling and membrane topography; 2) Abnormal signaling associated with carcinogenesis and cell survival (tyrosine kinase, Notch pathways) and 3) spatio-temporal modeling of cell signaling networks. 4) A newly funded project (Lidke) is focused on mast cell/dendritic cell interactions. Minimum requirement: Ph.D. in immunology, cell biology or biochemistry/molecular biology. Experience in the analysis of receptor-mediated signaling pathways using genetic, biochemical and/or microscopy techniques desired.
Please Send:
Your Curriculum Vitae
A Statement of Research Interest which includes the program for which you wish to be considered
Names of three References
To: Marie Chestnut, Search Coordinator
Pathology Department
MSC08 4640
1 University of New Mexico
Albuquerque, NM 87131
