Conducting Research with Animals

Animal Models

The choice of the proper animal model will be based upon several factors related to the nature of the disease or health issue. The role of genetics, disease susceptibility, size; and anatomical and physiological similarities should all be considered when choosing an animal that is best suited to the objectives of the research. The veterinary staff is available for consultation to assist the researcher in making the proper choice. Principles of humane animal research dictate that the researcher choose the least sentient species available that is appropriate for the research objectives.

Mice and Rats have become the most common animal models in biomedical research since the completion of the human, mouse, and rat genome projects. The following sites are recommended for genotype availability and phenotype information. These sites contain much useful information that is helpful when deciding upon an appropriate animal model:

Jackson Laboratories
Harlan- Sprague Dawley
Charles River Laboratories
Taconic M&B Laboratories