Cancer Biology & Epidemiology
Cancer biology or oncology, is the study of a large group
of diseases characterized by uncontrolled cell growth and spread of abnormal
cells. Research on many different types of cancer are investigated at
UNM including hematologic cancers, breast cancer, lung cancer, prostate
cancer, and skin cancer, as well as cancers of viral origin. The many
different exciting areas of cancer research at UNM include all aspects
of oncology encompassing carcinogenesis, cancer prevention, and cancer
treatment. Epidemiology is the branch of medicine that deals with the
study of the causes, distribution, and control of disease in populations.
Cancer epidemiology and prevention are key areas of epidemiological research
at UNM. Research in cancer biology and epidemiology at UNM are supported
by the UNM Cancer Research and Treatment Center, which was designated
by the National Cancer Institute.
David Bear, PhD
Regulation of mRNA biosynthesis and transport in muscular dystrophies
and muscle cell cancers; novel electron microscopy techniques to study
gene expression
Steve
Belinsky, PhD
Role of gene promoter hypermethylation lung cancer and use as a biomarker
for early detection
Marco Bisoffi,
PhD
Mechanisms of cancer metastasis, androgen independence in prostate cancer,
telomere biology
Susan
E. Boggs, PhD
Lung epithelial cellular responses to tobacco smoke
Tione Buranda,
PhD
Cellular biophysics and membrane structure
Scott
Burchiel, PhD
Immunotoxicity and carcinogenicity of environmental agents
Jeremy S. Edwards,
PhD
Spatial temporal modeling, epidermal growth factor receptor, functional
genomics technologies, sequencing
Linda
Felton, PhD
Drug delivery systems and pharmaceutics
Donald
Godwin, PhD
Development and testing of novel sunscreen formulations to prevent skin
cancer
Jeffrey
K. Griffith, PhD
Telomere biology, genetic polymorphisms and chromosome structure in cancer
Rebecca Hartley,
PhD
Post-transcriptional regulation of the cell cycle in cancer and embryogenesis
Helen Hathaway, PhD
Mammary gland development and breast cancer
Chien-An Andy
Hu, PhD
Programmed cell death (apoptosis and autophagy) in cancer and human genetic
disease, molecular enzymology of proline metabolism
Laurie
Hudson, PhD
Signal transduction pathways regulating functional and phenotypic plasticity
in normal tissue and tumor metastasis
Walt Kisiel,
PhD
Biochemistry of the initiation and regulation of blood coagulation; role
of coagulation in atherosclerosis, thrombosis, and cancer
Richard
Larson, MD/PhD
Cell adhesion and ligand design in the application to disease diagnosis,
biosensor design and imaging agent development
Diane Lidke,
PhD
Biophysical and live cell imaging approaches to study protein dynamics
and interactions during signal transduction
Jim Liu,
PhD
Free radical and oxidative stress in disease development, including carcinogenesis
and brain injury.
Joe
L. Mauderly, DVM
Health effects of air pollution
Jacob
McDonald, PhD
Implementation of analytical chemistry and aerosol science to address
questions of environmental relevance
Charlotte
Mobarak, PhD
Applications of proteomics to cancer research, cancer marker discovery
Scott A. Ness, PhD
Stem cells, oncogenes, signaling and the regulation of transcription,
differentiation and cell cycle
Jac A. Nickoloff, PhD
Molecular mechanisms of eukaryotic DNA repair with emphasis on DNA double-strand
break repair and its roles in maintaining genome stability and tumor suppression.
Janet Oliver,
PhD
IgE receptors of mast cells and basophils; spatio-temporal modeling of
signal transduction in allergy
and leukemogenesis
Robert A.
Orlando, PhD
Obesity and cardiovascular disease, proteoglycans, Alzheimer's disease,
angiogenesis
Mary Ann Osley, PhD
Histone modifications and the regulation of gene expression and DNA damage
repair
Michelle A. Ozbun,
PhD
Human papillomaviruses, animal papillomaviruses, cervical cancer, skin
cancer, epithelial biology, cancer biology, virology
David Peabody, PhD
RNA-protein interactions, translational regulation, virus assembly
Eric Prossnitz,
PhD
The Prossnitz lab focuses on cellular signaling mechanisms initiated by
G protein-coupled receptors.
Stephanie Ruby, PhD
RNA splicing, snRNPs, DEAD-box proteins, spliceosome, DNA-damage response,
cancer biology, genomics
Bobby
Scott, PhD
Mechanisms-based modeling of low-dose radiation and chemical-induced stochastic
effects (mutations, apoptosis, neoplastic transformation)
Laurel Sillerud,
PhD
Prostate cancer, metabolic regulation in tumors, biomedical NMR, cancer
metastasis
Larry Sklar,
PhD
GPCR signaling, integrins and cell adhesion, high throughput screening
using flow cytometry
Hugh D.
C. Smyth, PhD
Drug delivery and pharmaceutics
Yohannes
Tesfaigzi, PhD
Mechanisms underlying the proper regulation of cell numbers in airway
epithelia following inflammatory injury and their relation to chronic
diseases and cancers of the lung
Todd
A. Thompson, PhD
Investigate the molecular pathways in breast and prostate cancer development,
prevention, and treatment.
Graham
Timmins, PhD
Investigate the role of UV-induced radicals in melanoma; drug radicals
in antibiotic action
David L. Vander
Jagt, PhD
Structure-based drug design, molecular modeling, cancer research, diabetes
research
Dale
Walker, DVM
Evaluation of biomarkers of early toxic, genetic, and/or carcinogenic
changes in human and animal tissues, with special emphasis upon the effects
of exposure of lung tissue to low doses of chemicals or ionizing radiation
Vernon
Walker, DVM/PhD
The identification and validation of biological markers that are suitable
for investigating genotoxic mechanisms, determining human exposures, and
evaluating human cancer risks associated with exposure to chemicals in
the environment or as a consequence of medical therapy
Angela
Wandinger-Ness, PhD
Stem cells, kidney cell biology and mechanisms of protein trafficking
Cosette Wheeler,
PhD
Human papillomaviruses, cervical cancer, molecular epidemiology, vaccine
development
Cheryl
Willman, MD
Genomics and genetics of acute leukemia; genomics for molecular classification,
risk assessment, and target identification
Bridget
Wilson, PhD
Membrane microdomains, calcium signaling and modeling, signal transduction
Weihua Zeng, PhD
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