Cell Biology & Physiology
Cell Biology and Physiology research at UNM is a discipline that encompasses
research ranging from molecular studies of intracellular function to animal-based
studies of organ system function. The unifying feature of the group is
the study of integrated systems that encompass more than one enzyme, cell
type or organ system. Faculty members come from many academic backgrounds
including molecular, cellular and developmental biology, anatomy, biophysics,
biochemistry and physiology.
Research interests within the Group include:
Altitude and Hypoxia Related Diseases
Angiogenesis
Breast Cancer Biology and Development
Cell Cycle Regulation
Genetic Regulatory Networks
Melanoma and Skin Cancer
Multiple Sclerosis Research
Demyelinating Disorders
RNA trafficking
Cell Signaling and Trafficking
Vascular Physiology
Innovative Medical Education Paradigms
Andrea Allan, PhD
Prenatal drug and environmental exposure models; neural control of cognition;
learning and memory
Edward
G. Barrett, PhD
Fetal and infant immune maturation
David Bear, PhD
Regulation of mRNA biosynthesis and transport in muscular dystrophies
and muscle cell cancers; novel electron microscopy techniques to study
gene expression
Marco Bisoffi,
PhD
Mechanisms of cancer metastasis, androgen independence in prostate cancer,
telomere biology
Tione Buranda,
PhD
Cellular biophysics and membrane structure
Kevin Caldwell,
PhD
Signal transduction mechanisms underlying learning and memory
Matthew
Campen, PhD
How the cardiovascular system may become impaired as a result of insults
to the respiratory system
John Connor, PhD
Ca2+ and related second control of normal and degenerative responses in
brain neurons
Dusanka Deretic,
PhD
Biosynthesis, sorting and post-Golgi trafficking of rhodopsin to the rod
outer segments (ROS)
Vojo Deretic, PhD
Our latest interest is the process of Autophagy, an exciting new cell
homeostatic process that maintains the cellular interior (organelles and
cytosolic components) in a functional state, but sometimes can go awry
and cause cell death
Jeremy Edwards, PhD
Spatial temporal modeling, epidermal growth factor receptor, functional
genomics technologies, sequencing
Jeffrey
K. Griffith, PhD
Telomere biology, genetic polymorphisms and chromosome structure in cancer
Gary
Grotendorst, PhD
Biology of connective tissue growth factor (CTGF) as a regulator of cell
proliferation and differentiation
Rebecca Hartley,
PhD
Post-transcriptional regulation of the cell cycle in cancer and embryogenesis
Helen Hathaway, PhD
Mammary gland development and breast cancer
Chien-An Andy
Hu, PhD
Programmed celld eath (apoptosis and autophagy) in cancer and human genetic
disease, molecular enzymology of proline metabolism
Laurie
Hudson, PhD
Signal transduction pathways regulating functional and phenotypic plasticity
in normal tissue and tumor metastasis
Nancy Kanagy, PhD
Study of the mechanisms leading to altered vascular smooth muscle and
endothelial cell physiology in animal models of hypertension and sleep
apnea.
Diane Lidke,
PhD
Biophysical and live cell imaging approaches to study protein dynamics
and interactions during signal transduction
Craig
Marcus, PhD
Role of Cytochromes P450 in disease, cancer, and toxicology.
Paul McGuire, PhD
The role of extracellular proteinases and growth factors in the regulation
of ocular angiogenesis and vascular permeability.
Charlotte
Mobarak, PhD
Applications of proteomics to cancer research, cancer marker discovery
Janet Oliver,
PhD
IgE receptors of mast cells and basophils; spatio-temporal modeling of
signal transduction in allergy and leukemogenesis
Tudor Oprea,
MD/PhD
Drug discovery, cheminformatics, molecular modeling, virtual screening
Rob Orlando,
PhD
Obesity and cardiovascular disease, LDL receptor family, proteoglycans,
Alzheimer's disease
Karlett J. Parra, Ph.D.
Metabolic/nutritional control of proton transport/cellular pH by V-type
ATPase pumps, V-ATPase molecular motors structure/function/regulation.
Eric Prossnitz,
PhD
The Prossnitz lab focuses on cellular signaling mechanisms initiated by
G protein-coupled receptors.
Tom Resta, PhD
Mechanisms of chronic hypoxia-induced pulmonary hypertension.
Stephanie Ruby, PhD
RNA splicing, snRNPs, DEAD-box proteins, spliceosome, DNA-damage response,
cancer biology, genomics
Linda Saland, PhD
The effects of ethanol on brain opiate receptor expression and function
JeanClare
Seagrave, PhD
Mechanisms of health effects of inhaled materials including air pollution
and cigarette smoke
C. William Shuttleworth,
PhD
Mechanisms underlying degenerative calcium signaling in central neurons
Laurel Sillerud,
PhD
Prostate cancer, metabolic regulation in tumors, biomedical NMR, cancer
metastasis
Angela
Wandinger-Ness, PhD
Stem cells, kidney cell biology and mechanisms of protein trafficking
Bridget
Wilson, PhD
Membrane microdomains, calcium signaling and modeling, signal transduction
Michael Wilson, PhD
Molecular mechanisms of neurotransmission and its impact on brain development
and behavioral maturation
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