Biography
Dr. Alles completed his undergraduate degree in Biochemistry at Imperial College London and his PhD in Neuroscience at the University of Alberta with Prof Peter Smith, studying mechanisms of the gabapentinoid drugs for neuropathic pain. He then went on to complete Postdoctoral Fellowships at the University of British Columbia with Professor Terry Snutch and at University College London with Professor John Wood. His work has focused on understanding chronic pain mechanisms and ion channel biology, which has facilitated unique insights into novel therapeutics for treating pain, such as those impacting the ion channel NaV1.7.
Dr. Alles has extensive training in areas related to ion channel function and peripheral pain pathways in patients. His work has applied pre-clinical models, imaging, and electrophysiological and high-throughput molecular biology techniques to the study of the molecular mechanisms of chronic pain.
Given the high percentage (up to 50% over a lifetime) of our population suffering from chronic pain, the problems and well-known side effects associated with treating pain with opioids, and the dearth of alternative effective medications, Dr. Alles? work is of urgent need and has strong potential to create a paradigm shift in conventional treatments.
Areas of Specialty
Chronic pain, neuroscience, pharmacology, electrophysiology, imaging
Gender
Male