Areas of Specialty

Research Interests:

  • Chemical Biology
  • Structural Biology
  • X-ray crystallography
  • Drug discovery
  • Protein engineering

Education

  • B.S. Biophysics, 1997, Iowa State University of Science and Technology
  • M.S. Biochemistry, 1998, Iowa State University of Science and Technology
  • Ph.D. Biophysics, 2001, Iowa State University of Science and Technology
  • Post-doctoral Researcher, Chemistry, 2004, California Institute of Technology

Research and Scholarship

My main research interest is the structure-function relationship in carbohydrate-related and other proteins and its application to drug discovery, protein engineering and biotechnology. In our laboratory, we apply high-throughput methodologies for protein expression, functional analysis and crystallization. Besides x-ray protein crystallography, we routinely use membrane protein biochemistry, molecular biology and structural modeling.