Biography

McCance received a BS in Zoology in 1969 and a BS in Microbiology in 1971 from Queens University, Belfast and in 1974 a PhD in Microbiology from the University of Birmingham, UK.

Areas of Specialty

Oncology, virology, molecular biology, cell biology

Gender

Male

Research and Scholarship

Chesters, P.M., Heritage, J., McCance, D.J. (1983) Persistence of papovavirus (BK and JC) DNA sequences in normal human tissues and diseased tissues. J. Inf. Dis. 147:676-684.

McCance, D.J., Kopan, R., Fuchs, E.V., Laimins, L.A. (1988) Human papillomavirus type 16 alters human epithelial differentiation in vitro. Proc. Natl. Acad. Sci. (USA) 85:7169-7173.

McDade, SS. Henry, A. Pivato, GP. Fenwick, K. Assiotis, I.Kozarewa, I. Mitsopoulos, C. Hakas, J. Zvelebil, M. Orr, N. Lord, CJ. Ashworth, A.Patel, D. McCance, DJ. (2012) Genome wide identification of p63 binding sites reveals co-association of AP-2a on regulatory regions of genes required for palatal fusion. Nucleic Acid Res. 40(15):7190-206. doi:10.1093/nar/gks389. PMID: 22573176

McDade, SS., Patel, D., Moran, M., Campbell, J., Orr, NJ., Fenwick, K., Kozarewa, I., Lord, CJ., Ashworth, A., McCance, DJ. (2014) Genome wide characterization reveals complex interplay between TP53 and TP63 in response to genotoxic stress. Nucl. Acid Res. 42: 6270-6285. doi:10.1093/nar/gku299.PMID: 24823795

Craig SG, Anderson LA, Schache AG, Moran M, Graham L, Currie K, Rooney K, Robinson M, Upile NS, Brooker R, Mesri M, Bingham V, McQuaid S, Jones T, McCance DJ, Salto-Tellez M, McDade SS, James JA. Recommendations for determining HPV status in patients with oropharyngeal cancers under TNM8 guidelines: a two-tier approach. Br J Cancer. 2019 Apr;120(8):827-833. doi: 10.1038/s41416-019-0414-9. Epub 2019 Mar 20. PMID: 30890775