Biography
Vilay earned a B.Sc. in Pharmacy from the University of Alberta and a Pharm.D. from the University of Toronto. Following her Pharm.D. degree, she completed a 2 year critical care nephrology fellowship at the University of Michigan College of Pharmacy.
Personal Statement
The kidneys play an integral role with various organ systems in the body. Not only are the kidneys responsible for filtering waste products, they also play a key role in drug elimination, maintain fluid and electrolyte balance in the body, control red blood cell production, and support bone health. When patients develop kidney conditions, they are at risk of developing a number of complications related to the various functions that the kidneys are responsible for.
Currently, uncontrolled blood pressure and diabetes are the two most common causes of chronic kidney disease. High blood pressure and diabetes can be effectively managed with medications and lifestyle changes.
Pharmacist are well positioned to educate and assist patients in optimizing their medications to prevent kidney disease. If patients develop kidney disease, pharmacist may assist in the management of kidney disease related complications. Furthermore, pharmacists play a key role in adjusting medication doses so that medication continue to be effective while minimizing the risk of toxicities related to drug accumulation cause by decreased kidney elimination.
As a result, I am passionate about studying the elimination of drugs during kidney disease and developing strategies to optimize medication doses to improve patient health.
Areas of Specialty
Nephrology
Education
PharmD, University of Toronto, 2007
BSc. University of Alberta, 2000 (Pharmacy)
Key Publications
Journal Article
Vilay, Aloun, M Grio, M, Depestel, D, D Sowinski, K, M Gao, L, Heung, M, Salama, N, N Mueller, B, A 2011 Daptomycin pharmacokinetics in critically ill patients receiving continuous venovenous hemodialysis. Critical care medicine, vol. 39, Issue 1, 19-25
Journal Article
Vilay, Aloun, M Wong, C, S Schrader, R, M Mercier, Renee-Claude, Seifert, S, A 2013 Indicators for serious kidney complications associated with toxic exposures: an analysis of the National Poison Data System. Clinical toxicology (Philadelphia, Pa.), vol. 51, Issue 2, 96-105
Journal Article
Yardman-Frank, J, M Mercier, Renee-Claude, Wong, C, S Vilay, Aloun, M 2015 Iohexol transmembrane clearance during modeled continuous renal replacement therapy. Blood purification, vol. 39, Issue 1-3, 188-92
Journal Article
Devraj, R, Borrego, Matthew, E Vilay, Aloun, M Gordon, E, J Pailden, J, Horowitz, B, 2015 Relationship between Health Literacy and Kidney Function. Nephrology (Carlton, Vic.), vol. 20, Issue 5, 360-7
Journal Article
Dilworth, T, J Leonard, S, N Vilay, Aloun, M Mercier, Renee-Claude, 2014 Vancomycin and piperacillin-tazobactam against methicillin-resistant Staphylococcus aureus and vancomycin-intermediate Staphylococcus aureus in an in vitro pharmacokinetic/pharmacodynamic model. Clinical therapeutics, vol. 36, Issue 10, 1334-44
Research and Scholarship
Vilay?s research focuses on drug pharmacokinetics and pharmacodynamics in the setting of chronic kidney disease and acute kidney injury. Her goal is to optimize drug dosing, assessment of renal function, and delivery of renal replacement therapies in patients with kidney disease.