Biography
Dr. Yang received his BS from Peking University and his PhD from Peking Union Medical College. He was trained at University of Washington and M. D. Anderson Cancer Center.
Personal Statement
His research interests are in the regulation and function of T helper cells in immunity, autoimmunity, and inflammation. His published work can be found at:
https://www.ncbi.nlm.nih.gov/myncbi/xuexian.yang.1/bibliography/public/
Areas of Specialty
T helper cell
Asthma and pulmonary inflammation
Autoimmune
Transcriptional control
Signal transduction
Unfolded protein response
Achievements & Awards
Beginning Grant-in-Aid Award, American Heart Association (2009-2011)
Junior Faculty Travel Award, American Association of Immunologists (2010)
Obstructive Lung Disease Scholar, American Lung Association (2013-2015)
Research and Creative Works Leaders Award, University of New Mexico HSC (2025)
Key Publications
Journal Article
Park, H Li, Z Yang, Xuexian Chang, S H Nurieva, R Wang, Y H Wang, Y Hood, L Zhu, Z Tian, Q Dong, C A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nature immunology 10.1038/ni1261
Journal Article
Yang, Xuexian Pappu, B P Nurieva, R Akimzhanov, A Kang, H S Chung, Y Ma, L Shah, B Panopoulos, A D Schluns, K S Watowich, S S Tian, Q Jetten, A M Dong, C T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 10.1016/j.immuni.2007.11.016
Journal Article
Yang, Xuexian Zhang, H Kim, B S Niu, X Peng, J Chen, Y Kerketta, R Lee, Y H Chang, S H Corry, D B Wang, D Watowich, S S Dong, C The signaling suppressor CIS controls proallergic T cell development and allergic airway inflammation. Nature immunology 10.1038/ni.2633
Journal Article
Wu, Dandan Zhang, Xing Zimmerly, Kourtney M. Wang, Ruoning Wang, Chunqing Hunter, Russell Wu, Xiang Campen, Matthew Liu, Meilian Yang, Xuexian Unfolded protein response factor ATF6 augments T helper cell responses and promotes mixed granulocytic airway inflammation Mucosal Immunology 10.1016/j.mucimm.2023.05.007
Journal Article
Wu, D Zhang-resigned 10/2024, Xing Zimmerly, K M Wang, R Livingston, A Iwawaki, T Kumar - resign 12/31/25, Atul Wu, X Campen, M Mandell, Michael Liu, Meilian Yang, Xuexian Unconventional Activation of IRE1 Enhances TH17 Responses and Promotes Airway Neutrophilia. American journal of respiratory cell and molecular biology
Gender
Male
Courses Taught
Dr. Yang is a Co-Director of BioMed 514 Immunobiology (BSGP).
He also participates in teaching Microbiology and Immunology Block (UME).