The Department of Pathology pursues basic, clinical, translational, and population research via an array of individual faculty laboratories, leadership of research centers, and direction of core resources.
Bioaccumulation of microplastics in decedent human brains. Rising global concentrations of environmental microplastics and nanoplastics (MNPs) drive concerns for human exposure and health outcomes. Complementary methods for the robust detection of tissue MNPs, including pyrolysis gas chromatography... Read more.
A Melanoma Brain Metastasis CTC Signature and CTC:B-cell Clusters Associate with Secondary Liver Metastasis: A Melanoma Brain-Liver Metastasis Axis. Melanoma brain metastasis (MBM) is linked to dismal prognosis, low overall survival, and is detected in up to 80% of patients at autopsy. Circulating tumor cells... Read more.
Simultaneous multicolor fluorescence imaging using PSF splitting. We present a way to encode more information in fuorescence imaging by splitting the original point spread function (PSF), which ofers broadband operation and compatibility with other PSF engineering modalities and existing analysis tools... Read more.