Angelea Maestas-Olguin, PhD
ASERT Fellow
University of New Mexico School of Engineering
Dept. Chemical and Biological Engineering
Email angemaestas13@unm.edu
Education
Research
Angelea’s research focuses on designing biomaterials, specifically nanomaterials, for therapeutic drug and gene delivery in women’s health applications.
Research Mentors
Olivia Lanier, PhD, Department of Chemical and Biological Engineering, Department of Biomedical Engineering, and Department of Cell Biology and Physiology, University of New Mexico, Albuquerque, New Mexico 87106, United States; Cancer Therapeutics Program, University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico 87106, United States
Publications
Maestas-Olguin, A.; Olewine, M.; Thabata, S.; Tsala Ebode, J.; Arcos, M.; Krawchuck, J.; Coker, E. N.; Brearley, A. J.; Xue, X.; Watt, J.; Noureddine, A.; Brinker, C. J. Metallic Cation-Mediated Entrapment of Nucleic Acids on Mesoporous Silica Surface: Application in Castration-Resistant Prostate Cancer. Chem. Mater. 2023, 35(24), 10371–10383.
Noureddine, A.; Maestas-Olguin, A.; Tang, L.; Corman-Hijar, J.; Olewine, M.; Krawchuck, J.; Tsala Ebode, J.; Edeh, C.; Dang, C.; Negrete, Oscar A.; Watt, J.; Howard, T.; Coker, E.; Guo, J.; Brinker, C. J. Future of Mesoporous Silica Nanoparticles in Nanomedicine: protocol for reproducible synthesis, characterization, lipid coating and loading of therapeutics (chemotherapeutic, proteins, siRNA and mRNA). ACS Nano 2023.
Noureddine, A.; Maestas-Olguin, A.(co-first author); Saada, E. A.; LaBauve, A. E.; Agola, J. O.; Baty, K. E.; Howard, T.; Sabo, J. K.; Espinoza, C. R. S.; Doudna, J. A.; Schoeniger, J. S.; Butler, K. S.; Negrete, O. A.; Brinker, C. J.; Serda, R. E. Engineering of Monosized Lipid-Coated Mesoporous Silica Nanoparticles for CRISPR Delivery. Acta Biomaterialia 2020. Published online July 21, 2020.
El Hayek, E.; Medina, S.; Guo, J.; Noureddine, A.; Zychowski, K. E.; Hunter, R.; Velasco, C. A.; Wiesse, M.; Maestas-Olguin, A.; Brinker, C. J.; Brearley, A.; Spilde, M.; Howard, T.; Lauer, F. T.; Herbert, G.; Ali, A. M.; Burchiel, S.; Campen, M. J.; Cerrato, J. M. Uptake and Toxicity of Respirable Carbon-Rich Uranium-Bearing Particles: Insights into the Role of Particulates in Uranium Toxicity. Environ. Sci. Technol. 2021, 55 (14), 9949–9957.
Maestas-Olguin, A.; Dawson, M. M.; Quartey, E.; Ikwuemesi, P.; Lanier, O. L. Nanoparticle-Mediated Gene Therapy in Women’s Health: Progress, Delivery Challenges, and the Need for Sex, Age, and Ancestry Informed Design. ACS Biomater. Sci. Eng. 2025, 11 (7), 3949–4001.
Maestas-Olguin, A.; Dawson, M. M.; Clark, E. R.; Lanier, O. L. Emerging Nanotechnology-Enabled siRNA Oral Delivery Platforms. Nanomedicine 2025, 1–19. https://doi.org/10.1080/17435889.2025.2598337.