"From the Clinic to the Laboratory and Back"

Albuquerque, New Mexico
October 3rd and 4th 2018
Supported by: The Center for Brain Recovery and Repair
Funded by NIGMS Award 1P20GM109089

Program Agenda

An increased appreciation of the translational utility of electrophysiology has created new opportunities for comparing neural activity during behavior across species. Novel recording and analytic techniques afford the opportunity to develop methods for quantitative translation between species.

You are cordially invited to participate in a meeting of researchers and clinicians interested in increasing translation between clinical and preclinical studies utilizing electrophysiology as a theoretical and methodological hub for translation. This meeting offers the opportunity to share new findings and learn new techniques for novices and experts alike.

The meeting will include:

Presentations by leading researchers in human and rodent e-phys: Speakers will discuss approaches using e-phys and stereo-EEG in both human and rodents to examine neurophysiological correlates of behavior and disease.

• Christopher Lapish, Indiana University Purdue University Indianapolis
• Bita Moghaddam, Oregon Health Science University
• Andre Der-Avakian, University of California, San Diego
• James F. Cavanagh, University of New Mexico
• Julia Stephen, Mind Research Network
• Jill Silverman, University of California Davis
• Kaori Takehara, University of Toronto
• Jared Young, University of California, San Diego
• Steve Siegel, University of Southern California
• Jonathan Brigman, University of New Mexico
• Greg Light, University of California, San Diego
• Stephen Cowen, University of Arizona
• Mykel Robbie, Harvard University

Data Analysis Training Workshop: applying cutting-edge analytic techniques (e.g. spike-field coupling, wavelet decomposition, permutation testing) using open-source tools. Users must have at least beginner-level experience with Matlab (no basic programming will be taught). Bring your own laptop with Matlab installed.  Any version is fine, although use >2012 versions for best results.

• Hands-on training for time-series analysis using open data and open code.  All analyses are directly applicable to EEG, MEG, Local Fields, or any other time series in any species.
• We will take the user from raw data (provided) to a finished, statistically analyzed product.
• Analyses will include:
  • Time-frequency decomposition via wavelets and the Hilbert transform
  • Spike-field coupling for different statistical considerations
  • Directionality analysis (Granger, phase lag)
  • Statistical testing and multiple comparisons correction
• All concepts and code will be linked to existing online training resources for further independent study.  All analyses will include links to papers detailing some of the most recent controversies and considerations important for publishing in this field.

Interactive group roundtable: Discussion and questions with experts in the field regarding current issues in integrative and translational e-phys.

• Depth to dura to scalp: resolving oscillations across the brain.
• Spikes and fields: specific issues with individual and combined approaches.
• Publishing and funding: common issues with presenting e-phys data in multiple species, and potential mechanisms for funding this work.

Integrating rodent EEG with touch-screen assays:  Demonstration and training session for investigators interested in combing operant learning with electrophysiology.  

• Discuss and work through approaches for building and placement of both dura-resting and stereo/depth probes.
• Explore integration of behavioral systems with recording for high precision timing of discrete events (stimulus presentation, reward) that are important to your research.
• Discover ways to integrate high-precision video recording to examine e-phys activity over longer time windows, or during specific behaviors.
• Explore the Center for Brain Recovery and Repair and learn about resources available to assess behavior and integrate e-phys in your research projects through the Preclinical Core.

Poster session: Join scientists at all levels to discuss recent findings and new opportunities on Wednesday evening, October 3rd.

• Network with other scientists and discuss opportunities and roadblocks in the field.
• Discover multiple approaches to integrating e-phys with behavior across species.
• Enjoy networking in a relaxed atmosphere at the boutique Hotel Parq Central.

Travel awards are available for investigators from IDeA states: The UNM Center for Brain Recovery and Repair is making competitive travel funds available.

• Open to investigators from Institutional Development Award Program states.
• Investigators at all levels (Faculty, Postdoc and Students) are eligible.
• Travel awardees must submit a poster abstract to be eligible.

For questions concerning the meeting or registration please contact:

Christina Klauber
Program Administrator, Center for Brain Recovery and Repair
klauber@salud.unm.edu

Jonathan Brigman
Associate Director, CBRR Preclinical Core
jbrigman@salud.unm.edu

"Pushing the boundaries of clinical science"

Albuquerque, New Mexico
October October 4^th-6^th 2017
Supported by: The Center for Brain Recovery and Repair and Dr. Vince Clark, PhD (Dept. of Psychology) 

October 4^th

The Hands-on Transcranial Direct Current Stimulation (tDCS) Course was led by Drs. Marom Bikson, Helena Knotkova, and Adam Woods. Over 55 registrants and attendees participated in the didactic and practical training in using transcranial direct stimulation with overwhelmingly positive support indicating that they thoroughly enjoyed the experience.

October 5^th- 6^th

Approximately 115 registrants and attendees were treated with keynote lectures by the founders and leading researchers in neurostimulation.

Presentations by researchers in neurostimulation:

• Michael Nitsche, MD
• Bashar Badran, PhD
• Marom Bikson, PhD
• Vince Clark, PhD
• Bernadette Gillick, PhD
• John George, PhD
• Roy Hamilton, MD, MS
• Helena Knotkova, PhD
• Phil, MD
• Min-Fang Kuo, PhD
• Sarah Pirio Richardson, MD
• Davin Quinn, MD
• Jay Sanguinetti, PhD
• Claudia Tesche, PhD
• Danny Wang, PhD, MSCE
• Eric Wasserman, MD
• Katie Witkewitz, PhD
• Adam Woods, PhD

Attendees also enjoyed a reception and poster session held at the Hotel Parq Central which provided the opportunity to meet and network with researchers and clinicians interested in the use of neurostimulation techniques for research and clinical purposes. Researchers and clinicians from across the US, Canada, Germany, and Russia were in attendance.  We were pleased to provide travel support to individuals from Institutional Development Award (IDeA) programs, including the University of South Dakota School of Medicine, Louisiana State University, Brown University, and the University of Nebraska Medical Center.