Delivering an ultrasensitive biomarker measurement that you can count on.
The Simoa HD-X Analyzer™ is the latest model of the fully automated Simoa bead-based immunoassay platform. Reengineered, the platform's ultrasensitivity and dependability empower researchers with 1000x greater sensitivity than traditional immunoassays. HD-X Analyzer can be used to measure biomarkers in human and animal samples (serum, plasma, CSF, and brain lysates).
The HD-X is the world’s most sensitive, fully automated immunoassay platform with multiplexing and custom assay capabilities. Using a bead-based immunoassay platform, the new flagship HD-X Analyzer delivers major productivity enhancements, greater user flexibility, unparalleled sensitivity, and best-in-class assay performance across a broad assay selection to empower biomarker research and accelerate drug development.
Ultra-Sensitivity
The HD-X has an average of 1000x greater sensitivity than traditional immunoassays. Quanterix’s digital biomarker detection technology is giving researchers the ability to examine critical proteins and nucleic acids at ultra low, sometimes baseline, levels, in most common sample types.
Automation
Running traditional immunoassays is a largely manual process, making it a time-consuming task. The HD-X Analyzer performs all steps of the assay (other than loading your plate/loading the machine) which not only improves the efficiency of running the immunoassay, but also minimizes the variability of results common in manual approaches.
Multiplexing
The HD-X Analyzer is capable of measuring up to 6 biomarkers in a single assay. This provides sample preservation without sacrificing sensitivity or precision.
Precision
Due to the digital nature of the HD-X and the consistency through automation, CV’s are below 10%
Dynamic Range
The proprietary algorithm uses both digital measurements at low concentrations and analog measurements at higher concentrations, allowing a remarkable dynamic range of >4 logs.
Homebrew Assays
Quanterix helps users develop and optimize their own assays to be run on the HD-X Analyzer.
Full Service
Everything is handed to our research staff (plate layout, samples, supplies, and Simoa Kit), a staff member will run the full experiment and return the data to you.
Partial Service
An already prepped plate is handed to our research staff, along with a plate layout, supplies, and the Simoa Kit, they insert items into the HD-X, and return the data to you.
The disk packs (plates, tips, disks, and cuvettes) run about $1,144.50 each and the buffer sets are $270.00 each based on rates from Spring 2023. Disk packs and buffer set pricing constantly changing. Please refer to Quanterix website for current pricing.
All users must submit a signed MOU for each project.
Download Quanterix MOU template.
| Rate per Run | Estimate Costs per Run | |
|---|---|---|
| Service Fee* |
UNM rate: $150/h x 2 h to run 1 kit Non-UNM rate: $250/h x 2 h to run 1 kit |
UNM: $300 per kit Non-UNM: $500 per kit |
| Disk pack |
1 disk pack is good for 4 kits |
$1,144.50 per disk pack |
| Buffer Sets |
1 buffer set is good for 4 kits |
$270 per buffer set |
| Subtotal: |
$1,714.50 (UNM $1,914.50 (Non-UNM) |
*Service fee is for maintenance and usage based on similar service offered at other universities. For examples, visit UT Southwestern and UCLA-Health.
Pricing for kits from Quanterix is not included and it depends on what kind of kits the investigator is interested in running. Please visit their website for details: https://www.quanterix.com/simoa-assay-kits/
Running everything in duplicate: (8 Standards X 2) + (2 Controls X 2) + (38 Samples X 2) = 96 Test
If you are running less than 38 samples (not the entire plate) or do not plan to purchase supplies (disk pack and buffer sets), then the service fee is $15/sample (UNM) and $20/sample (non-UNM).
Dr. Kiran Bhaskar
Co-Director, UNM Brain and Behavioral Health Institute
Co-Director, UNM New Mexico Alzheimer's Disease Research Center (Exploratory)
Associate Professor, UNM Molecular Genetics and Microbiology
Phone: (505) 272-1230
Email: kbhaskar@salud.unm.edu
Gary Rosenberg, MD
Professor, UNM Neurology,
Director, UNM Center for Memory and Aging
Phone: 505-277-3215
Email: GRosenberg@salud.unm.edu
Sasha Hobson
Senior Research Specialist
UNM Center for Memory & Aging
Phone: (505) 272-8010
Email: sahobson@health.unm.edu
Physical Address:
Pete and Nancy Domenici Hall
Room Numbers: 1311
1101 Yale Blvd NE
Albuquerque, NM 87106-0001, USA
Mailing Address:
Attn: Dr. Kiran Bhaskar
Domenici Hall
MSC08 4660
1 University of New Mexico
Albuquerque, NM 87131-0001, USA
Shipping Address:
Attn: Sasha Hobson
915 Camino de Salud NE
Domenici Hall 260 R1311
Albuquerque , NM 87131, USA
Publications containing assay results, data, images or products generated by the core require citation in the acknowledgment section of the paper to include the core name, core personnel and any grants that directly support core operations. Core specific information is below:
Sample Acknowledgement Statement:
This research was supported by UNM Department of Molecular Genetics & Microbiology (MGM)/Brain & Behavioral Health Institute (BBHI) & Quanterix HD-X Analyzer Core, Grant No. NIH RF1NS083704-05A1.
Principle Investigators
Kiran Bhaskar, PhD
Gary Rosenberg, MD