mPI Publications

Alicia Bolt, PhD  

  1. Tungsten targets the tumor microenvironment to enhance breast cancer metastasis. Bolt AM, Sabourin V, Molina MF, Police AM, Negro Silva LF, Plourde D, Lemaire M, Ursini-Siegel J, Mann KK.Toxicol Sci. 2015 Jan;143(1):165-77. doi: 10.1093/toxsci/kfu219. Epub 2014 Oct 15.PMID: 25324207 Free PMC article.
  2. Tungsten Promotes Sex-Specific Adipogenesis in the Bone by Altering Differentiation of Bone Marrow-Resident Mesenchymal Stromal Cells. Bolt AM, Grant MP, Wu TH, Flores Molina M, Plourde D, Kelly AD, Negro Silva LF, Lemaire M, Schlezinger JJ, Mwale F, Mann KK.Toxicol Sci. 2016 Apr;150(2):333-46. doi: 10.1093/toxsci/kfw008. Epub 2016 Feb 9.PMID: 26865663 Free PMC article.
  3. VanderSchee C, Kuter D, Bolt AM, Mann KK, Lo FC, Wiegert-Chen K, Thieme J, Williams G, Feng R, and Bohle S. (2018) Accumulation and transformation of tungstate in bone: In situ generation of robust and persistent polytungstate. Comm. Chemistry. 1:8 March 8th  
  4. Analyzing the Tumor Microenvironment by Flow Cytometry. Young YK, Bolt AM, Ahn R, Mann KK.Methods Mol Biol. 2016;1458:95-110. doi: 10.1007/978-1-4939-3801-8_8.PMID: 27581017
  5. Tungsten: an Emerging Toxicant, Alone or in Combination. Bolt AM, Mann KK.Curr Environ Health Rep. 2016 Dec;3(4):405-415. doi: 10.1007/s40572-016-0106-z.PMID: 27678292 Review.
  6. Tungsten Blocks Murine B Lymphocyte Differentiation and Proliferation Through Downregulation of IL-7 Receptor/Pax5 Signaling. Wu TH, Bolt AM, Chou H, Plourde D, De Jay N, Guilbert C, Young YK, Kleinman CL, Mann KK.Toxicol Sci. 2019 Jul 1;170(1):45-56. doi: 10.1093/toxsci/kfz080.PMID: 30912803


Xiang Xue, PhD  

  1. Zheng W, Ma Z, Sun X, Huang Y, Lu B, Chen X, Xue X#, Yang X#, Wu X#. Exposure time determines the protective effect of Trichinella spiralis on experimental colitis. Microb Pathog. 2020;May 20;147:104263. PMID: 32442663 (# Co-corresponding author)
  2. Xue X#, Falcon DM. The role of immune cells and cytokines in intestinal wound healing. Int. J. Mol. Sci. 2019, 20(23), 6097. (# Corresponding author)
  3. Kim H, Yin K, Falcon DM, Xue X#. The interaction of Hemin and Sestrin2 modulates oxidative stress and colon tumor growth. Toxicol Appl Pharmacol. 2019 Jul 1; 374, 77-85. PMID: 31054940. PMCID: PMC6613364 (# Corresponding author)
  4. Xue X #, Bredell BX, Anderson ER, Martin A, Mays C, Nagao-Kitamoto H, Huang S, Győrffy B, Greenson JK, Hardiman K, Spence JR, Kamada N, Shah YM#. Quantitative Proteomics Identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9608-E9617. PMID: 29078383 (# Corresponding author)
  5. Xue X, Shah YM. Iron, Cancer and HIF Signaling. Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals. Chapter 17. 2016 Sep 29; 203-213. Academic Press.
  6. Xue X, Ramakrishnan S, Weisz K, Triner D, Xie L, Győrffy B, Zhan M, Carter-Su C, Hardiman KM, Dame M, Varani J, Brenner D, Fearon ER, Shah YM. Iron Uptake via DMT1 Integrates Cell Cycle with JAK-STAT3 Signaling to Promote Colorectal Tumorigenesis. Cell Metab. 2016. Sep 13;24(3)447-461. PMID: 27546461 (Selected as a Cover Article and highlighted by the journal with a commentary article “The Irony of Tumor-Induced Inflammation. Cell Metab. 2016. Sep 13;24(3)368-369”)


Rama Gullapalli, MD, PhD

  1. Sharma P, Caldwell TS, Rivera MN, Gullapalli RR. Cadmium exposure activates Akt/ERK Signaling and pro-inflammatory COX-2 expression in human gallbladder epithelial cells via a ROS dependent mechanism. Toxicol In Vitro. 2020 Sep;67:104912. doi: 10.1016/j.tiv.2020.104912. Epub 2020 Jun 6. PubMed PMID: 32512147; NIHMSID:NIHMS1604853.
  2. Martin DR, Hanson JA, Gullapalli RR, Schultz FA, Sethi A, Clark DP. A Deep Learning Convolutional Neural Network Can Recognize Common Patterns of Injury in Gastric Pathology. Arch Pathol Lab Med. 2020 Mar;144(3):370-378. doi: 10.5858/arpa.2019-0004-OA. Epub 2019 Jun 27. PubMed PMID: 31246112.
  3. Gullapalli RR. Evaluation of Commercial Next-Generation Sequencing Bioinformatics Software Solutions. J Mol Diagn. 2020 Feb;22(2):147-158. doi: 10.1016/j.jmoldx.2019.09.007. Epub 2019 Nov 18. PubMed PMID: 31751676; PubMed Central PMCID: PMC7031678.
  4. Nemunaitis JM, Brown-Glabeman U, Soares H, Belmonte J, Liem B, Nir I, Phuoc V, Gullapalli RR. Gallbladder cancer: review of a rare orphan gastrointestinal cancer with a focus on populations of New Mexico. BMC Cancer. 2018 Jun 18;18(1):665. doi: 10.1186/s12885-018-4575-3. Review. PubMed PMID: 29914418; PubMed Central PMCID: PMC6006713.
  5. Martin DR, LaBauve E, Pomo JM, Chiu VK, Hanson JA, Gullapalli RR. Site-Specific Genomic Alterations in a Well-Differentiated Pancreatic Neuroendocrine Tumor With High-Grade Progression. Pancreas. 2018 Apr;47(4):502-510. doi: 10.1097/MPA.0000000000001030. PubMed PMID: 29521944; PubMed Central PMCID: PMC5884111.
  6. Pomo JM, Taylor RM, Gullapalli RR. Influence of TP53 and CDH1 genes in hepatocellular cancer spheroid formation and culture: a model system to understand cancer cell growth mechanics. Cancer Cell Int. 2016;16:44. doi: 10.1186/s12935-016-0318-1. eCollection 2016. PubMed PMID: 27303212; PubMed Central PMCID: PMC4907104.


Xixi Zhou, PhD

  1. Bethany Sanchez, Xixi Zhou, Amy S. Gardiner, Guy Herbert, Selita Lucas, Masako Morishita, James G. Wagner, Ryan Lewandowski, Jack R. Harkema, Chris Shuey, Matthew J. Campen, Katherine E. Zychowski. Serum-borne factors alter cerebrovascular endothelial microRNA expression following particulate matter exposure near an abandoned uranium mine on the Navajo Nation. Part Fibre Toxicol. 2020; 17: 29. Published online  Jul 1. doi: 10.1186/s12989-020-00361-3. 2020.
  2. Zhou, KL. Cooper, X. Sun, KJ. Liu & LG. Hudson “Selective Sensitization of Zinc Finger Protein Oxidation by ROS Through Arsenic Binding” J. Biol. Chem. M115. 663906 (2015)
  3. Wang, X. Zhou, W. Liu, X. Sun, C. Chen, LG. Hudson & KJ. Liu “Arsenite-induced ROS/RNS generation causes zinc loss and inhibits the activity of poly(ADP-ribose) polymerase-1.” Free Radic. Biol. Med. 61, 249–256 (2013). (Equally Contributed)
  4. Zhou, X. Sun, KL. Cooper, F. Wang, KJ. Liu & LG. Hudson, “Arsenite interacts selectively with zinc finger proteins containing C3H1 or C4 motifs.” J. Biol. Chem. 286, 22855–22863 (2011).
  5. Zhou, P. Han, X. Zhang, B. Huang, H. Ruan & C. Chen, “ESNOQ, proteomic quantification of endogenous S-nitrosation.” PLoS ONE 5, e10015 (2010).
  6. Zhou, X. Sun, C. Mobarak, AJ. Gandolfi, SW. Burchiel, LG. Hudson & KJ. Liu “Differential binding of monomethylarsonous acid compared to arsenite and arsenic trioxide with zinc finger peptides and proteins.” Chem. Res. Toxicol. 27(4), 690-698 (2014)