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Amanda Barkley-Levenson, Ph.D. Behavioral pharmacology; genetics of alcohol use disorder and related psychiatric disorders; novel therapeutic targets for alcohol use disorder |
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Effects of environmental pollutants on adaptive immune responses in immune-mediated inflammatory disorders; T cell epigenetics; role of gut microbiome in xenobiotic-induced autoimmunity |
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Mechanisms of metal-enhanced tumorigenesis; role of the tumor microenvironment to drive tumor promotion; metal immunotoxicity |
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Cardiovascular health effects of inhaled substances along with basic research on vascular pathophysiology |
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Methicillin-resistant Staphylococcus aureus (MRSA) infections, including host-pathogen interactions, sex-bias, vaccine development using VLPs, and small molecule inhibitors of quorum sensing. |
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Asthma pathogenesis and its response to environmental agents; rethinking approaches in biogeochemistry to understand bioavailability and health exposure; community-driven agricultural research for metals exposure |
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Autoimmune molecular markers; Tribal community-based participatory research; integration of human immune responses with exposure to metals and xenobiotics |
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Modified release drug delivery; polymeric film coating; formulation development and manufacturing drug products for clinical trials |
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Roles of metals in life processes with an emphasis on molecular mechanisms of nitric oxide synthase isoform regulation |
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Scholarship of teaching and learning with emphasis on innovative methods to enhance problem solving and critical thinking |
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Host defense against methicillin-resistant Staphylococcus aureus and therapeutic interventions targeting MRSA virulence |
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Regulation of epithelial plasticity in metastasis and wound repair; novel therapeutics for ovarian cancer; mechanisms of arsenic carcinogenesis |
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Effects of metals exposures in tribal populations, metals toxicology, and intervention design and implementation |
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Immunotoxicology of metals and metal exposures in populations; Experimental therapeutics for prostate cancer and melanoma |
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Drug delivery in cancer, infection, and other diseases; pulmonary drug delivery; nanomedicine; buccal drug delivery |
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Mechanisms of metal-induced toxicity to hematopoietic stem and progenitor cells, including the hematotoxicity of inorganic and organic arsenicals. Other research areas focus on elucidating mechanisms of immune dysregulation produced by metal and other toxicant exposures. |
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Applied molecular genetics and molecular imaging aimed at therapeutic targeting of hyperglycemia in diabetes with common comorbidities like atherosclerosis. Clinical and translational interventions in diabetic vasculopathy and health disparities |
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Formulation, characterization, and preclinical evaluation of vaccines and drugs via the oral, pulmonary, and transdermal routes. |
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Experimental therapeutics for cancer; toxicity of androgenic endocrine disruptors; drug discovery; pharmacogenomics |
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Stable isotope compounds for the diagnosis and treatment of infectious diseases; role of UV-induced radicals in melanoma |